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Review
. 1982 Feb;12(1):3-17.
doi: 10.1016/s0195-5616(82)50001-0.

Review of glucocorticoid pharmacology

Review

Review of glucocorticoid pharmacology

J R Wilcke et al. Vet Clin North Am Small Anim Pract. 1982 Feb.

Abstract

Rational glucocorticoid therapy depends on a complicated interplay of many factors. An understanding of the physiology of the hypothalamic-pituitary-adrenal axis, the comparative potencies, duration, and adverse effects of the available corticosteroid bases and their esters, and especially the specific goals of the therapy for a wide variety of diseases facilitates this therapy. It is impossible to make specific dose recommendations for glucocorticoid therapy. Individual patients and their various diseases respond differently to a given dose of glucocorticoid.

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