IgG subclass levels in malaria-infected Nigerians

Abstract

IgG class and subclass levels were measured in the sera of malaria-infected patients who had high serum antibody titres (greater than or equal to 1 in 5,120) as well as in uninfected controls with low serum malaria antibody titres (less than or equal to 1 in 320). The malaria-infected patients had higher IgG and IgGI subclass levels than the uninfected controls (p less than 0.005). There was a slight diminution in the mean IgG3 concentration in the malaria-infected patients.