Requirement of Fnr and NarL functions for nitrate reductase expression in Escherichia coli K-12
- PMID: 7050087
- PMCID: PMC220410
- DOI: 10.1128/jb.151.3.1320-1325.1982
Requirement of Fnr and NarL functions for nitrate reductase expression in Escherichia coli K-12
Abstract
I used a chlC-lac operon fusion to study regulatory mutations which affect nitrate reductase expression in Escherichia coli. A NarL- mutant apparently lacks a nitrate-specific positive regulatory component. Furthermore, an fnr (nirR) mutation prevented enzyme induction under any conditions. These data are consistent with a two-step, positive control model for nitrate reductase regulation.
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