Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1982 Aug;35(8):815-9.
doi: 10.1136/jcp.35.8.815.

Lysozyme in chronic liver disease: a biochemical and histological study

I H Manifold, F M Bishop, P Cloke, D R Triger, J C Underwood

Lysozyme in chronic liver disease: a biochemical and histological study

I H Manifold et al. J Clin Pathol. 1982 Aug.

Abstract

Serum lysozyme activities and semiquantitative analysis of tissue lysozyme distribution were studied in patients with primary biliary cirrhosis (PBC), chronic hepatitis (CH), miscellaneous liver diseases, and normal subjects. Serum lysozyme was significantly raised in PBC and CH. Portal venous blood has similar lysozyme activities to peripheral venous blood in a group of various liver diseases. Lysozyme-containing intralobular cells were decreased in all liver diseases studied but portal tract lysozyme was increased only in PBC and CH. Thus the increase in serum lysozyme in PBC and CH appears to originate from the portal inflammatory infiltrate, seen in these diseases.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Gut. 1979 Jan;20(1):55-8 - PubMed
    1. Proc Soc Exp Biol Med. 1968 Feb;127(2):365-7 - PubMed
    1. Biochim Biophys Acta. 1952 Mar;8(3):302-9 - PubMed
    1. Immunology. 1975 Jun;28(6):1099-114 - PubMed
    1. Ter Arkh. 1971 Aug;43(8):26-30 - PubMed

Publication types