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. 1982 Jan;28(1):75-8.

Gas-chromatographic determination of ethylene glycol in serum

W H Porter, A Auansakul
  • PMID: 7055939

Gas-chromatographic determination of ethylene glycol in serum

W H Porter et al. Clin Chem. 1982 Jan.

Abstract

We describe a new gas-chromatographic procedure for ethylene glycol in serum, determined as the cyclic phenylboronate ester. The method is rapid, requires only 100 microL of serum, and either an OV-1 or an OV-17 column is used. The linear dynamic range extends to at least 5000 mg/L, with a lower limit of detection of 10 mg/L. Analytical recovery of ethylene glycol from serum averaged 97% (95-101%) over the concentration range of 250-5000 mg/L. The method demonstrates good precision, with CVs less than 2.5%, over the concentration range 500-2000 mg/L.

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