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. 1982 Apr;13(4):539-41.
doi: 10.1111/j.1365-2125.1982.tb01418.x.

The addition of prazosin to standard triple therapy in the treatment of severe hypertension

A M Heagerty, G I Russell, R F Bing, H Thurston, J D Swales

The addition of prazosin to standard triple therapy in the treatment of severe hypertension

A M Heagerty et al. Br J Clin Pharmacol. 1982 Apr.

Abstract

1 A small dose of prazosin was added to the treatment regime of sixteen hypertensive patients poorly controlled on a combination of bendrofluazide, hydralazine and propranolol. 2 There was a significant improvement in blood pressure control in all patients at 1 month (P less than 0.01) and this was maintained at 9 months (P less than 0.02). Tolerance to prazosin was not a problem. 3 The addition of prazosin to conventional triple drug therapy produces a further useful fall in blood pressure.

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