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Comparative Study
. 1978 Oct;70(4):623-7.
doi: 10.1093/ajcp/70.4.623.

Diagnostic problems involved in detection of metastatic neoplasms by bone-marrow aspirate compared with needle biopsy

R A Savage, G C Hoffman, K Shaker
Comparative Study

Diagnostic problems involved in detection of metastatic neoplasms by bone-marrow aspirate compared with needle biopsy

R A Savage et al. Am J Clin Pathol. 1978 Oct.

Abstract

Diagnostic problems involved in detection of metastatic neoplasms by bone-marrow aspirate compared with needle biopsy. Am J Clin Pathol 70: 623--627, 1978. Comparison of a large series of bone marrow aspirations with simultaneously performed Jamshidi needle biopsies showed 75% correlation between the two procedures for detection of metastatic neoplasms. In cases where the two methods disagreed, false-negative aspirations resulting from perineoplastic desmoplasia was the usual reason for the discrepancy. Cytologic criteria for the evaluation of suspected neoplastic cells in aspirate preparations are discussed.

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