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. 1982 Mar;363(3):341-3.

Determination of reduced biopterins by high pressure liquid chromatography and subsequent electrochemical detection

M Bräutigam, R Dreesen, H Herken
  • PMID: 7076129

Determination of reduced biopterins by high pressure liquid chromatography and subsequent electrochemical detection

M Bräutigam et al. Hoppe Seylers Z Physiol Chem. 1982 Mar.

Abstract

L-erythro-Tetrahydrobiopterin plays an important role as the cofactor of various hydroxylation reactions. We report here the separation of biopterin and its reduced forms by reversed-phase high pressure liquid chromatography. Subsequent electrochemical detection yields a sensitivity at the picomole level for dihydrobiopterin and tetrahydrobiopterin.

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