Periaqueductal gray matter involvement in the muscimol-induced decrease of morphine antinociception
- PMID: 7078669
- DOI: 10.1007/BF00501180
Periaqueductal gray matter involvement in the muscimol-induced decrease of morphine antinociception
Abstract
Microinjections of muscimol, a GABA receptor agonist, into the periaqueductal gray matter (PAG) counter-acted the antinociceptive effect of morphine in rats, as measured by the "tail-flick" method. Muscimol's effect was partially reversed by bicuculline.
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