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. 1982 Mar;318(4):368-9.
doi: 10.1007/BF00501180.

Periaqueductal gray matter involvement in the muscimol-induced decrease of morphine antinociception

Periaqueductal gray matter involvement in the muscimol-induced decrease of morphine antinociception

F Zambotti et al. Naunyn Schmiedebergs Arch Pharmacol. 1982 Mar.

Abstract

Microinjections of muscimol, a GABA receptor agonist, into the periaqueductal gray matter (PAG) counter-acted the antinociceptive effect of morphine in rats, as measured by the "tail-flick" method. Muscimol's effect was partially reversed by bicuculline.

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