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. 1978 Sep;14(3):315-7.
doi: 10.1128/AAC.14.3.315.

Pharmacokinetics of cefamandole in infants and children

S H Walker, V P Gahol

Pharmacokinetics of cefamandole in infants and children

S H Walker et al. Antimicrob Agents Chemother. 1978 Sep.

Abstract

In infants less than 3 months of age, the serum concentration of cefamandole during therapy was higher and more prolonged than that in children older than 1 year. A dosage of 37 mg/kg administered intravenously at 6-h intervals provided a serum concentration in excess of the minimum inhibitory concentrations of common bacterial pathogens for 4 h, and in young infants for 5 h, after dosing.

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