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Comparative Study
. 1982 Apr;52(4):995-9.
doi: 10.1152/jappl.1982.52.4.995.

Problems in measurement of thoracic gas volume in infancy

C S Beardsmore, J Stocks, M Silverman
Comparative Study

Problems in measurement of thoracic gas volume in infancy

C S Beardsmore et al. J Appl Physiol Respir Environ Exerc Physiol. 1982 Apr.

Abstract

Thoracic gas volume (TGV) was measured with a whole-body plethysmograph in 20 infants at functional residual capacity (FRC) and at a series of higher lung volumes achieved by artificial inflation of the lungs with known volumes of air after airway occlusion. There was a discrepancy between the corrected values of TGV measured at high and low lung volumes in nine infants; in six cases TGV measured at high lung volumes exceeded that measured at FRC, and in three cases it was reduced when compared with the measurement made at FRC. These changes were not related to age, size, or clinical status and could be explained by airway closure at FRC, combined with an uneven distribution of pleural pressure.

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