doi: 10.1038/bjc.1978.224.
Measurement of oestradiol receptors by five institutions on common tissue samples
- PMID: 708574
- PMCID: PMC2009740
- DOI: 10.1038/bjc.1978.224
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Measurement of oestradiol receptors by five institutions on common tissue samples
Br J Cancer.
1978 Sep.
Free PMC article
Abstract
The soluble oestrogen-receptor content of common breast tumours has been measured by 5 different laboratories, each using their own assay procedure. Good agreement was achieved on whether a sample was positive or negative for oestrogen receptor. Qualitative differences between laboratories could be explained by differences in thiol-reagent content of assay medium and by the method of homogenization. Recommendations are made on some of the factors involved in the routine assay of receptors in breast tumours.
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