Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1982 Jun;35(6):606-10.
doi: 10.1136/jcp.35.6.606.

Villous atrophy with crypt hyperplasia in malignant histiocytosis of the nose

K Aozasa

Villous atrophy with crypt hyperplasia in malignant histiocytosis of the nose

K Aozasa. J Clin Pathol. 1982 Jun.

Abstract

Intestinal changes, mainly in the jejunum, were investigated in 13 cases of malignant histiocytosis at necropsy and who had presented as lethal midline granuloma. Villous atrophy with crypt hyperplasia was observed in all cases, and a proliferation of atypical histiocytes was observed in seven cases. In the remaining cases, histiocytes with normal morphology increased in number. These findings showed that a prolonged abnormal proliferation of histiocytes was present in the small intestine of these cases concurrently with the nasal lesions.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Am J Surg. 1966 Oct;112(4):597-605 - PubMed
    1. Cancer. 1969 Apr;23(4):920-35 - PubMed
    1. Arch Otolaryngol. 1972 May;95(5):467-76 - PubMed
    1. Cancer. 1975 Jan;35(1):215-30 - PubMed
    1. Am J Gastroenterol. 1975 Feb;63(2):129-34 - PubMed