doi: 10.1021/jm00347a016.
Structure--activity relationships of nogalamycin analogues
- PMID: 7086843
- DOI: 10.1021/jm00347a016
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Structure--activity relationships of nogalamycin analogues
J Med Chem.
1982 May.
Abstract
Nogalamycin (1) has been modified by changes at C-10 and C-7 and in the dimethylamino group to prepare an extensive series of analogues. The chemistry involved in the modifications and structure--activity relationships among these nogalamycin analogues are discussed, as well as comparisons with previously reported compounds 1, 7-con-O-methylnogarol (2), and disnogamycin (11).
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