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Comparative Study
. 1982 Mar;82(3):60-6.

[Mechanism of folliculogenesis in the rat thyroid in long-term hypercalcemia]

[Article in Russian]
N P Fedchenko
  • PMID: 7092592
Comparative Study

[Mechanism of folliculogenesis in the rat thyroid in long-term hypercalcemia]

[Article in Russian]
N P Fedchenko. Arkh Anat Gistol Embriol. 1982 Mar.

Abstract

Two types of folliculogenesis specific for the peripheral and central zones of the rat thyroid gland under prolonged hypercalcemia are described. The folliculogenesis is realized via fragmentation of a large follicle into several small ones penetrated with cords of the connective tissue. The new follicles are formed with various intensity. When the folliculogenesis is intensive, a distinctly seen desquamation of the follicular epithelium is observed. Thyrocalcitonin secreted by C-cells is probably the initiative factor of the folliculogenesis. A suggestion is made on a leading role of C-cells in pathogenesis of the goiter.

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