[Passage through the mitotic cycle of ascitic hepatoma 22A cells under unfavorable artificially created conditions]

Abstract

The author studied the changes in the mitotic cycle of ascites hepatoma 22A cells under artificially created unfavourable conditions. It was shown that as a result 3 tumors of 6-day development united. In the early stage of such a union there was a blockade in passage from G1 in S period and from G2 in mitosis. The cells which were in S period at the moment of union accumulated in G2 period and passed to the irreversible resting state. In the course of the union the cells in G1 period completely preserved the ability to complete the mitotic cycle.