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. 1982 Jun;76(2):245-52.
doi: 10.1111/j.1476-5381.1982.tb09213.x.

The action of porcine glucagon on the motility of the canine duodenum and jejunum

D F Evans, G E Foster, J D Hardcastle, F Jonhson, J W Wright

The action of porcine glucagon on the motility of the canine duodenum and jejunum

D F Evans et al. Br J Pharmacol. 1982 Jun.

Abstract

1 Intravenous bolus doses of porcine glucagon of 0.001-0.05 mg kg-1 caused intense stimulation of the duodenum and jejunum of the dog. 2 Intravenous infusion of porcine glucagon at 0.025-0.05 mg kg-1 h-1 caused similar stimulation. In both cases the stimulation was phasic in nature. 3 Stimulation of the duodenum and jejunum following glucagon was accompanied by a decrease in frequency of the intestinal basic electrical rhythm (BER). No change was seen in the intervals between successive periods of phase III motor activity.

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