Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 1982 Jan;47(1):197-205.

C3b inactivator deficiency with immune complex manifestations

P Solal-Celigny, M Laviolette, J Hebert, P C Atkins, M Sirois, G Brun, G Lehner-Netsch, J M Delâge
Case Reports

C3b inactivator deficiency with immune complex manifestations

P Solal-Celigny et al. Clin Exp Immunol. 1982 Jan.

Abstract

We report a complete C3b inactivator deficiency in a 28-year-old patient referred for bronchiectasis and recurrent pneumonia. In addition to these recurrent infections, previously described with this deficiency, he also had several immune complex manifestations (rheumatoid factor, circulating immune complexes and one episode of serum sickness). The consequences of C3b inactivator deficiency on complement activation, chemotaxis and opsonization, clearance of immune complexes, and on red blood cell sensitization are discussed. The study of the parents showed an autosomal dominant transmission.

PubMed Disclaimer

References

    1. J Immunol. 1968 Jun;100(6):1154-64 - PubMed
    1. J Clin Invest. 1970 Nov;49(11):1975-85 - PubMed
    1. J Immunol. 1971 Jul;107(1):19-27 - PubMed
    1. Proc Natl Acad Sci U S A. 1972 Oct;69(10):2910-3 - PubMed
    1. Biomedicine. 1973 Aug 10;19(8):353-60 - PubMed

Publication types

Substances

LinkOut - more resources