doi: 10.1111/j.1398-9995.1977.tb01348.x.
Cyclic AMP and allergic histamine release. Influence of methylxanthines on rat mast cells
- PMID: 70945
- DOI: 10.1111/j.1398-9995.1977.tb01348.x
Item in Clipboard
Cyclic AMP and allergic histamine release. Influence of methylxanthines on rat mast cells
Acta Allergol.
1977 Jun.
Abstract
Both isobutylmethylxanthine and theophylline increased the level of cyclic AMP in rat mast cells. Theophylline reduced the allergic histamine release, whereas isobutylmethylxanthine caused a pronounced potentiation of the histamine release. This indicates that the hypothesis of an inverse relationship between the level of cyclic AMP in mast cells and histamine release is inadequate.
Similar articles
-
Allergic reactions, cyclic AMP and histamine release.Experientia. 1977 Jul 15;33(7):965-6. doi: 10.1007/BF01951308. Experientia. 1977. PMID: 70374
-
[Biochemical and pharmacological control of allergic histamine release].Patol Fiziol Eksp Ter. 1976 Nov-Dec;(6):5-11. Patol Fiziol Eksp Ter. 1976. PMID: 65763 Russian. No abstract available.
-
On the mechanism by which theophylline inhibits histamine release from rat mast cells.Acta Physiol Scand. 1982 Feb;114(2):243-51. doi: 10.1111/j.1748-1716.1982.tb06978.x. Acta Physiol Scand. 1982. PMID: 6182749
-
Cyclic nucleotide involvement in histamine release from mast cells--a reevaluation.Life Sci. 1982 Jan 18;30(3):213-8. doi: 10.1016/0024-3205(82)90501-x. Life Sci. 1982. PMID: 6175875 Review.
-
Pharmacologic modulation of inflammatory mediator release by rat mast cells.Am J Pathol. 1976 Nov;85(2):437-64. Am J Pathol. 1976. PMID: 63247 Free PMC article. Review.
Cited by
-
Role of adenylate cyclase in immunologic release of mediators from rat mast cells: agonist and antagonist effects of purine- and ribose-modified adenosine analogs.Proc Natl Acad Sci U S A. 1980 Nov;77(11):6800-4. doi: 10.1073/pnas.77.11.6800. Proc Natl Acad Sci U S A. 1980. PMID: 6256761 Free PMC article.
-
Differentiation between cyclic AMP level and allergic histamine release in mast cells [proceedings].Agents Actions. 1979 Apr;9(1):64-5. doi: 10.1007/BF02024115. Agents Actions. 1979. PMID: 88891 No abstract available.
-
Effects of [N-(2-oxo-3,5,7-cycloheptatrien-1-yl)] aminooxoacetic acid ethyl ester (AY-25,674) on cyclic 3',5'-nucleotide formation and phosphodiesterase activity.Experientia. 1979 Jan 15;35(1):88-90. doi: 10.1007/BF01917895. Experientia. 1979. PMID: 217716
-
The human lung mast cell.Environ Health Perspect. 1984 Apr;55:259-69. doi: 10.1289/ehp.8455259. Environ Health Perspect. 1984. PMID: 6428878 Free PMC article. Review.