[Effects of timolol maleate on untreated contralateral eyes (author's transl)]

Abstract

The efficacity of installations of 0,5 p. cent timolol maleate unilaterally was statistically evaluated in 15 subjects: 5 with open-angle glaucoma, 5 with secondary glaucoma, and 5 normal subjects. A reduction in intraocular pressure was observed in all cases, not only in treated eyes, but also, though to a lesser degree, in untreated eyes. Effects were almost totally lacking on lacrimal secretion, corneal sensitivity, and pupil size in both eyes. The hypothesis is raised of possible unilateral treatment in selected patients with ocular hypertension and/or trabecular glaucoma.