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Case Reports
. 1982 Mar;58(677):175-7.
doi: 10.1136/pgmj.58.677.175.

Atrio-ventricular block after administration of lignocaine in patients treated with prenylamine

E Grenadier, G Alpan, S Keidar, A Palant
Case Reports

Atrio-ventricular block after administration of lignocaine in patients treated with prenylamine

E Grenadier et al. Postgrad Med J. 1982 Mar.

Abstract

Four patients are described who exhibited prolonged Q-T intervals, multiple ventricular premature beats and ventricular tachycardia of the ‘torsade de pointes’ configuration whilst on treatment with prenylamine. In two of these patients, advanced atrio-ventricular block was established immediately following intravenous administration of lignocaine. The arrhythmia and the atrio-ventricular blocks were successfully controlled by ventricular pacing. The hazard of the simultaneous administration of these two drugs is stressed.

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