Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 1982 Mar;58(677):175-7.
doi: 10.1136/pgmj.58.677.175.

Atrio-ventricular block after administration of lignocaine in patients treated with prenylamine

E Grenadier, G Alpan, S Keidar, A Palant
Case Reports

Atrio-ventricular block after administration of lignocaine in patients treated with prenylamine

E Grenadier et al. Postgrad Med J. 1982 Mar.

Abstract

Four patients are described who exhibited prolonged Q-T intervals, multiple ventricular premature beats and ventricular tachycardia of the ‘torsade de pointes’ configuration whilst on treatment with prenylamine. In two of these patients, advanced atrio-ventricular block was established immediately following intravenous administration of lignocaine. The arrhythmia and the atrio-ventricular blocks were successfully controlled by ventricular pacing. The hazard of the simultaneous administration of these two drugs is stressed.

PubMed Disclaimer

References

    1. N Engl J Med. 1967 Dec 7;277(23):1215-9 - PubMed
    1. Am J Cardiol. 1970 Jan;25(1):1-5 - PubMed
    1. Am J Cardiol. 1973 Feb;31(2):277-81 - PubMed
    1. Cardiovasc Res. 1972 Nov;6(6):664-70 - PubMed
    1. Br Heart J. 1973 Mar;35(3):305-11 - PubMed

Publication types