Behaviour of hematoporphyrin and protoporphyrin with antidepressant drugs
- PMID: 7100241
Behaviour of hematoporphyrin and protoporphyrin with antidepressant drugs
Abstract
Complexation between oppositely charged antidepressant drugs and porphyrin derivatives was investigated by NMR spectroscopy. The solid complexes obtained are soluble in antidepressant aggregates and a good fit was found between the values of CMC of the drugs and the values of the binding constants of porphyrins with antidepressant micelles.
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