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. 1978 Sep;6(8):673-8.

Population sizes of granulocyte-macrophage and monocyte-macrophage colony-forming cells in Sl/Sld

K F McCarthy, T J MacVittie
  • PMID: 710547

Population sizes of granulocyte-macrophage and monocyte-macrophage colony-forming cells in Sl/Sld

K F McCarthy et al. Exp Hematol. 1978 Sep.

Abstract

The sizes of granulocyte-macrophage (CFU-c) and monocyte-macrophage (CFC) progenitor cell populations were measured and compared in Sl/Sld and +/+ mice. In the marrow, the CFU-c and CFC population sizes were 40% and 67%, respectively, of the +/+ marrow CFU-c and CFC population sizes. There was no difference in the size of these two-cell populations in the spleens or thymi of Sl/Sld mice as compared with +/+ mice. Furthermore, the marrow CFC population was found to be heterogeneous by velocity sedimentation. One of the marrow CFC subpopulations is characterized by a velocity sedimentation value of 5.05 mm/h while the other has a value of 6.30 mm/h.

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