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. 1982 Feb;38(2):448-50.
doi: 10.1111/j.1471-4159.1982.tb08649.x.

Fluorometrical analysis of guanidino compounds in human cerebrospinal fluid

A Mori, Y Watanabe, N Fujimoto

Fluorometrical analysis of guanidino compounds in human cerebrospinal fluid

A Mori et al. J Neurochem. 1982 Feb.

Abstract

Guanidino compounds in CSF of 57 human subjects were determined fluorometrically after reaction with phenanthrenequinone in alkali solution, using HPLC. Creatinine (65.2 +/- 13.4 nmol/ml), arginine (24.7 +/- 6.4 nmol/ml), and homoarginine (0.7 +/- 0.3 nmol/ml) were found in all subjects. Trace amounts of guanidinosuccinic acid and guanidinoacetic acid were detected in some of the subjects. Brain guanidino compounds, taurocyamine, N-acetylarginine, and methylguanidine were not detected in CSF.

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