Vascularization and radiocurability in cancer of the uterine cervix. A retrospective study
- PMID: 7110445
Vascularization and radiocurability in cancer of the uterine cervix. A retrospective study
Abstract
The proportion of vascular elements in relation to the parenchymal and stromal components was determined by morphometric analysis of the histologic preparations from biopsies of uterine cervix cancers. In all cases, the material was obtained from tumors in Stages Ib and IIa before any therapy was initiated. In the 23 cases in which radiation treatment of the lesions resulted in a survival longer than 5 years, the proportion of blood vessels in the neoplastic tissue was found to be larger, and especially the stromal components were richer in vascular elements than in the 22 cases in which survival was shorter than 5 years. It was concluded that vascular density at least in cervical cancers of the stages studied can be a diagnostic parameter of a prognostic value as well as of a therapeutic usefulness.
Similar articles
-
Prognostic significance of vascular density and a malignancy grading in radiation treated uterine cervix carcinoma.Neoplasma. 1988;35(3):289-96. Neoplasma. 1988. PMID: 3405337
-
The relevance of the TDF and CRE concepts in combined radiation treatment of early cancer of the cervix uteri.Radiobiol Radiother (Berl). 1986;27(1):17-23. Radiobiol Radiother (Berl). 1986. PMID: 3704123 No abstract available.
-
Tumor vascularization, hypoxia, staging of tumors and radiocurability.Strahlentherapie. 1984 Nov;160(11):658-60. Strahlentherapie. 1984. PMID: 6506102
-
Present status of radium.N Y State J Med. 1974 May;74(5):822-4. N Y State J Med. 1974. PMID: 4208487 Review. No abstract available.
-
[The most recent trends in treatment of cancer of the cervix].Ann Osp Maria Vittoria Torino. 1978 Jul-Dec;21(7-12):151-202. Ann Osp Maria Vittoria Torino. 1978. PMID: 399163 Review. Italian. No abstract available.
Cited by
-
The vascular architecture of human xenotransplanted tumors: histological, morphometrical, and ultrastructural studies.J Cancer Res Clin Oncol. 1990;116(5):517-24. doi: 10.1007/BF01613005. J Cancer Res Clin Oncol. 1990. PMID: 2229144 Free PMC article.
-
Tumour vascularity is a significant prognostic factor for cervix carcinoma treated with radiotherapy: independence from tumour radiosensitivity.Br J Cancer. 1999 Sep;81(2):354-8. doi: 10.1038/sj.bjc.6690700. Br J Cancer. 1999. PMID: 10496365 Free PMC article.
-
Vascularization and curability of stage III and IV nasopharyngeal tumors.J Cancer Res Clin Oncol. 1988;114(3):321-3. doi: 10.1007/BF00405843. J Cancer Res Clin Oncol. 1988. PMID: 3384847 Free PMC article.
-
Changes in tumour morphology with alterations in oxygen availability: further evidence for oxygen as a limiting substrate.Br J Cancer. 1991 Jul;64(1):54-8. doi: 10.1038/bjc.1991.238. Br J Cancer. 1991. PMID: 1854627 Free PMC article.
-
Angiogenesis is associated with vascular endothelial growth factor expression in cervical intraepithelial neoplasia.Br J Cancer. 1997;76(11):1410-5. doi: 10.1038/bjc.1997.571. Br J Cancer. 1997. PMID: 9400935 Free PMC article.