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. 1978 Sep;13(9):95-8, 103-4, 106.
doi: 10.1080/21548331.1978.11707401.

Drug-induced liver injury

J R Mitchell, B H Lauterburg

Drug-induced liver injury

J R Mitchell et al. Hosp Pract. 1978 Sep.

Abstract

In the usual course of events, the liver detoxifies hepatocytotoxic intermediates of drug metabolism. But when protective systems are overloaded by normally harmless drugs, the intermediates can cause massive, even fatal, hepatic necrosis.

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