doi: 10.1080/21548331.1978.11707401.
Drug-induced liver injury
- PMID: 711216
- DOI: 10.1080/21548331.1978.11707401
Item in Clipboard
Drug-induced liver injury
Hosp Pract.
1978 Sep.
Abstract
In the usual course of events, the liver detoxifies hepatocytotoxic intermediates of drug metabolism. But when protective systems are overloaded by normally harmless drugs, the intermediates can cause massive, even fatal, hepatic necrosis.
Similar articles
-
[Drug-induced liver damage; new aspects on its mechanism].Duodecim. 1980;96(5):394-402. Duodecim. 1980. PMID: 6893817 Finnish. No abstract available.
-
Metabolic activation: biochemical basis for many drug-induced liver injuries.Prog Liver Dis. 1976;5:259-79. Prog Liver Dis. 1976. PMID: 775543 Review. No abstract available.
-
Liver disease caused by medicinal agents.Med Clin North Am. 1975 Jul;59(4):897-907. doi: 10.1016/s0025-7125(16)31988-5. Med Clin North Am. 1975. PMID: 1142866 No abstract available.
-
Drug metabolism in the production of liver injury.Med Clin North Am. 1975 Jul;59(4):877-85. doi: 10.1016/s0025-7125(16)31986-1. Med Clin North Am. 1975. PMID: 238084 Review. No abstract available.
-
Drug-related acute and chronic hepatitis.Clin Gastroenterol. 1980 Jan;9(1):213-24. Clin Gastroenterol. 1980. PMID: 6994951 Review. No abstract available.
Cited by
-
Avoidance and management of adverse reactions to antituberculosis drugs.Drug Saf. 1995 Jan;12(1):1-25. doi: 10.2165/00002018-199512010-00001. Drug Saf. 1995. PMID: 7741981 Review.