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. 1978 Sep;21(3):1024-6.
doi: 10.1128/iai.21.3.1024-1026.1978.

Specific binding of staphylococcal alpha-toxin to isolated rabbit vagus nerves in vitro

S Szmigielski, S Harshman

Specific binding of staphylococcal alpha-toxin to isolated rabbit vagus nerves in vitro

S Szmigielski et al. Infect Immun. 1978 Sep.

Abstract

The binding of staphylococcal [125I]alpha-toxin to rabbit vagus nerves in vitro was a saturable process. The radiolabeled alpha-toxin binding was reduced by the coaddition of added navive alpha-toxin, indicating that the binding is specific. Sucrose gradient analysis of detergent-extracted complexes of [125I]alpha-toxin-rabbit vagus nerves showed both high and low S-value peaks analogous to those observed with similarly treated alpha-toxin-rabbit erythrocyte preparations (P. Cassidy and S. Harshman, Biochemistry, in press).

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