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. 1978 Oct;12(4):217-21.
doi: 10.1111/j.1399-3011.1978.tb02889.x.

Inhibition of thrombin and trypsin by tripeptide aldehydes

S Bajusz, E Barabás, P Tolnay, E Széll, D Bagdy

Inhibition of thrombin and trypsin by tripeptide aldehydes

S Bajusz et al. Int J Pept Protein Res. 1978 Oct.

Abstract

Inhibitory effects of certain tripeptide aldehydes on both thrombin and trypsin have been found to be strongly substrate-dependent. These compounds should therefore be considered as inhibitors of the particular proteolytic reaction for which they had been designed rather than real enzyme inhibitors, i.e. protein or polypeptide proteinase inhibitors of natural origin.

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