Effects of immobilization and partial denervation on the differentiation of muscle fiber types in the Zebrafish, Brachydanio rerio
- PMID: 7114489
- DOI: 10.1007/BF00301879
Effects of immobilization and partial denervation on the differentiation of muscle fiber types in the Zebrafish, Brachydanio rerio
Abstract
In this study we tested the effects of immobilization and of spinal cord lesion on the differentiation of muscle fiber types in the myotomal muscle of the zebrafish. We found that the differentiation of embryonic red and white muscle fibers occurs in immobilized as well as in denervated myotomes of zebrafish embryos. Intermediate and adult red muscle fibers are not formed in denervated myotomes of larvae. Adult zebrafishes with spinal cord lesions in the anal region show abnormal undulating movements in the rostral part of the body. This change in muscle activity correlates with an increase in the number of intermediate scattered fibers. We conclude that direct contact with spinal cord motorneurons is not necessary for the differentiation of embryonic red and white fibers. The differentiation of intermediate muscle fibers is under extrinsic control. The factors that determine the formation of adult red fibers are not yet clear.
Similar articles
-
The development of the spinal motor column in relation to the myotomal muscle fibers in the zebrafish (Brachydanio rerio). I. Posthatching development.Anat Embryol (Berl). 1983;167(1):125-39. doi: 10.1007/BF00304606. Anat Embryol (Berl). 1983. PMID: 6881540
-
Differentiation of muscle fiber types in the teleost Brachydanio rerio, the zebrafish. Posthatching development.Anat Embryol (Berl). 1982;164(1):51-62. doi: 10.1007/BF00301878. Anat Embryol (Berl). 1982. PMID: 7114488
-
Identification of motoneurons in the spinal cord of the zebrafish (Brachydanio rerio), with special reference to motoneurons that innervate intermediate muscle fibers.Anat Embryol (Berl). 1990;182(1):93-102. doi: 10.1007/BF00187531. Anat Embryol (Berl). 1990. PMID: 2240597
-
Activation of embryonic red and white muscle fibers during fictive swimming in the developing zebrafish.J Neurophysiol. 2002 Mar;87(3):1244-51. doi: 10.1152/jn.00659.2001. J Neurophysiol. 2002. PMID: 11877498
-
Development of segmentation in zebrafish.Development. 1988;104 Suppl:197-207. doi: 10.1242/dev.104.Supplement.197. Development. 1988. PMID: 3077108 Review.
Cited by
-
An open source microcontroller based flume for evaluating swimming performance of larval, juvenile, and adult zebrafish.PLoS One. 2018 Jun 26;13(6):e0199712. doi: 10.1371/journal.pone.0199712. eCollection 2018. PLoS One. 2018. PMID: 29944715 Free PMC article.
-
The development of the spinal motor column in relation to the myotomal muscle fibers in the zebrafish (Brachydanio rerio). I. Posthatching development.Anat Embryol (Berl). 1983;167(1):125-39. doi: 10.1007/BF00304606. Anat Embryol (Berl). 1983. PMID: 6881540
-
Reexpression of myogenic proteins in mature electric organ after removal of neural input.J Neurosci. 1998 Dec 1;18(23):9924-35. doi: 10.1523/JNEUROSCI.18-23-09924.1998. J Neurosci. 1998. PMID: 9822748 Free PMC article.
-
Properties of skeletal muscle in the teleost Sternopygus macrurus are unaffected by short-term electrical inactivity.Physiol Genomics. 2016 Sep 1;48(9):699-710. doi: 10.1152/physiolgenomics.00068.2016. Epub 2016 Jul 22. Physiol Genomics. 2016. PMID: 27449658 Free PMC article.