Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1982 Aug;41(4):414-6.
doi: 10.1136/ard.41.4.414.

Lymphocyte cytotoxicity in systemic sclerosis: no increase on short-term culture with established human cell lines

J K Wright, P Hughes, N R Rowell

Lymphocyte cytotoxicity in systemic sclerosis: no increase on short-term culture with established human cell lines

J K Wright et al. Ann Rheum Dis. 1982 Aug.

Abstract

Lymphocyte cytotoxicity towards 4 established human epithelial and fibroblast cell lines was investigated in 18 patients with systemic sclerosis by means of both whole blood and peripheral blood mononuclear cells in short term (18 h) Cr-release assays. No difference in the levels of cytotoxicity was found in patients compared with 25 normal controls, even when allowance was made for the severity of the disease and the sex of patients and controls. It is suggested that long-term (3-6 days) culture may be necessary to demonstrate the increased lymphocyte cytotoxicity originally described in the disorder.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Lancet. 1966 Feb 26;1(7435):452-4 - PubMed
    1. Arthritis Rheum. 1968 Oct;11(5):607-17 - PubMed
    1. Br J Dermatol. 1971 May;84(5):400-9 - PubMed
    1. Lancet. 1975 Feb 15;1(7903):363-6 - PubMed
    1. J Clin Invest. 1976 Dec;58(6):1388-94 - PubMed

Publication types