doi: 10.1016/0005-2795(77)90156-8.
Antibodies against protein antigenic sites that are identical in the homologous protein of the immunized animal. Autoreactivity in rabbits of antibodies to sperm-whale myoglobin
- PMID: 71166
- DOI: 10.1016/0005-2795(77)90156-8
Item in Clipboard
Antibodies against protein antigenic sites that are identical in the homologous protein of the immunized animal. Autoreactivity in rabbits of antibodies to sperm-whale myoglobin
Biochim Biophys Acta.
.
Abstract
Sequence comparisons between the antigenic sites of sperm-whale myoglobin and the corresponding regions in rabbit myoglobin indicate that rabbits make antibodies to regions of the sperm-whale myoglobin molecule which are identical to the corresponding regions in rabbit myoglobin. Rabbit myoglobin did not precipitate with antisera to sperm-whale myoglobin. However, it exhibited an extensive cross-reaction as demonstrated by its ability to inhibit the precipitin reaction of sperm-whale myoglobin, and on an immunoadsorbent, bound a large amount of antibodies to sperm-whale myoglobin.
Similar articles
-
The antibody response to myoglobin is independent of the immunized species. Analysis in terms of replacements in the antigenic sites and in environmental residues of the cross-reactions of fifteen myoglobins with sperm-whale myoglobin antisera raised in different species.Biochem J. 1980 Dec 1;191(3):681-97. doi: 10.1042/bj1910681. Biochem J. 1980. PMID: 6169338 Free PMC article.
-
First consequences of the determination of the entire antigenic structure of sperm-whale myoglobin.Adv Exp Med Biol. 1978;98:19-40. doi: 10.1007/978-1-4615-8858-0_3. Adv Exp Med Biol. 1978. PMID: 82383
-
Antigenic structure of sperm whale myoglobin. I. Partition of specificities between antibodies reactive with peptides and native protein.J Immunol. 1982 Jul;129(1):206-11. J Immunol. 1982. PMID: 7086130
-
The antigenic structure of myoglobin and initial consequences of its precise determination.CRC Crit Rev Biochem. 1979;6(4):337-69. doi: 10.3109/10409237909105425. CRC Crit Rev Biochem. 1979. PMID: 88297 Review. No abstract available.
-
Antigenic structure of myoglobin: the complete immunochemical anatomy of a protein and conclusions relating to antigenic structures of proteins.Immunochemistry. 1975 May;12(5):423-38. doi: 10.1016/0019-2791(75)90010-5. Immunochemistry. 1975. PMID: 53189 Review. No abstract available.
Cited by
-
Antigenic structure of human haemoglobin. Localization of the antigenic sites of the beta-chain in three host species by synthetic overlapping peptides representing the entire chain.Biochem J. 1986 Mar 1;234(2):441-7. doi: 10.1042/bj2340441. Biochem J. 1986. PMID: 2424430 Free PMC article.
-
Precise determination of protein antigenic structures has unravelled the molecular immune recognition of proteins and provided a prototype for synthetic mimicking of other protein binding sites.Mol Cell Biochem. 1980 Aug 29;32(1):21-43. doi: 10.1007/BF00421293. Mol Cell Biochem. 1980. PMID: 6160381 Review.
-
Structurally inherent antigenic sites. Localization of the antigenic sites of the alpha-chain of human haemoglobin in three host species by a comprehensive synthetic approach.Biochem J. 1982 Apr 1;203(1):201-8. doi: 10.1042/bj2030201. Biochem J. 1982. PMID: 6179509 Free PMC article.
-
The antibody response to myoglobin is independent of the immunized species. Analysis in terms of replacements in the antigenic sites and in environmental residues of the cross-reactions of fifteen myoglobins with sperm-whale myoglobin antisera raised in different species.Biochem J. 1980 Dec 1;191(3):681-97. doi: 10.1042/bj1910681. Biochem J. 1980. PMID: 6169338 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
