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Comparative Study
. 1982 May;18(5):495-500.
doi: 10.1007/BF02796479.

Carnitine transport in cultured muscle cells and skin fibroblasts from patients with primary systemic carnitine deficiency

C J Rebouche, A G Engel
Comparative Study

Carnitine transport in cultured muscle cells and skin fibroblasts from patients with primary systemic carnitine deficiency

C J Rebouche et al. In Vitro. 1982 May.

Abstract

L-Carnitine transport was studied in cultured muscle cells and skin fibroblasts of patients with primary systemic carnitine deficiency and control subjects. In both cell culture types, two systems for carnitine transport were identified. The kinetic parameters for carnitine transport were remarkably similar in cultured muscle cells and skin fibroblasts. Normal rates and kinetic properties of carnitine transport were observed for both cell lines from patients with systemic carnitine deficiency. These studies do not rule out a defect in carnitine transport in vivo.

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References

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