Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1982 Feb;7(2):221-7.
doi: 10.1007/BF00965060.

The regional distribution of manganese in the normal human brain

E Bonilla, E Salazar, J J Villasmil, R Villalobos

The regional distribution of manganese in the normal human brain

E Bonilla et al. Neurochem Res. 1982 Feb.

Abstract

The concentration of manganese per gram dry tissue weight was determined in samples from 39 areas of 8 normal human brains. Manganese was shown to be unevenly distributed with the largest concentrations in the pineal gland and the olfactory bulb. The gray matter yielded a higher content of manganese than the white matter. Significant differences between individuals were found for identical areas of the gray and white matter of the cerebral cortex. Higher levels of manganese were demonstrated in the tail of the caudate nucleus than in the body and the head of the same structure. No significant correlation was shown between the amount of manganese in brain and age.

PubMed Disclaimer

References

    1. J Clin Invest. 1971 Jan;50(1):9-20 - PubMed
    1. Adv Neurol. 1976;14:339-52 - PubMed
    1. Med Clin North Am. 1976 Jul;60(4):729-38 - PubMed
    1. Arch Neurol. 1974 Jan;30(1):59-64 - PubMed
    1. Br J Pharmacol Chemother. 1962 Apr;18:370-80 - PubMed

Publication types