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Comparative Study
. 1982 Jun;7(6):657-66.
doi: 10.1007/BF00965519.

Localization of monoamine oxidases A and B in primate brains relative to neuron-specific and non-neuronal enolases

I C Campbell, P J Marangos, A Parma, N A Garrick, D L Murphy
Comparative Study

Localization of monoamine oxidases A and B in primate brains relative to neuron-specific and non-neuronal enolases

I C Campbell et al. Neurochem Res. 1982 Jun.

Abstract

Using serotonin and phenylethylamine deamination as measures of MAO A and MAO B activity respectively, positive correlations were observed between the activities of MAO A and MAO B in different areas of rhesus monkey and human brains. When the activities of MAO A and MAO B were compared with those of neuron-specific enolase and nonneuronal enolase (isozymes which are markers for neurons and glia), a slight but non-significant correlation was observed, suggesting that a simple distribution of MAO A in neurons and MAO B in glia is unlikely. This conclusion is supported by studies using synaptosomes, but contrasts with that from investigations of MAO from peripheral tissues, where experiments indicate that MAO A is predominantly localized in neurones.

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