Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1982 Apr-Jun;3(2):127-36.
doi: 10.1016/s0143-4004(82)80046-5.

Placental transfer and metabolism of purines and nucleosides in the pregnant guinea pig

B K van Kreel, J P van Dijk, A M Pijnenburg

Placental transfer and metabolism of purines and nucleosides in the pregnant guinea pig

B K van Kreel et al. Placenta. 1982 Apr-Jun.

Abstract

The placental transfer and metabolism of several purines and nucleosides have been investigated using an artificially perfused guinea-pig placenta. A model describing transfer and metabolism in the uteroplacental unit is constructed and applied. Measurements of oxypurines and guanine have been performed in vivo in the blood of pregnant guinea pigs and their fetuses. It appears that only the oxypurines and, to a lesser extent, guanine are present in the maternal and fetal circulations. These purines could be involved in transfer from mother to fetus and used for salvage in the fetal tissues.

PubMed Disclaimer

LinkOut - more resources