Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1982 Sep;34(5):811-7.

Genetic evidence for the inactivation of a human autosomal locus attached to an inactive X chromosome

T Mohandas, R S Sparkes, L J Shapiro

Genetic evidence for the inactivation of a human autosomal locus attached to an inactive X chromosome

T Mohandas et al. Am J Hum Genet. 1982 Sep.

Abstract

Mouse-human cell hybrid clones retaining an inactive translocated chromosome involving the human X and 13 were isolated. Esterase D, a marker on the segment of chromosome 13 translocated to the X, was not expressed in these clones. These results provide genetic evidence for the spreading of inactivation into the autosomal segment in an inactive human X-autosome translocation.

PubMed Disclaimer

References

    1. Nature. 1961 Apr 22;190:372-3 - PubMed
    1. Proc Natl Acad Sci U S A. 1962 Dec 15;48:2026-34 - PubMed
    1. Science. 1964 Aug 14;145(3633):709-10 - PubMed
    1. J Lab Clin Med. 1969 Mar;73(3):531-4 - PubMed
    1. Biochem Genet. 1969 Apr;3(2):189-95 - PubMed

Publication types

LinkOut - more resources