Case Reports
[Ovarian insufficiency and galactosemia]
[Article in
French]
- PMID: 7125830
Item in Clipboard
Case Reports
[Ovarian insufficiency and galactosemia]
[Article in
French]
Arch Fr Pediatr.
1982 May.
Abstract
A primitive gonadal failure was observed in 2, 20 and 18 years old galactosemic female patients. The conditions was clinically suspected because of primary amenorrhea in one case and delayed puberty, followed by spaniomenorrhea in the other case, and confirmed by very low plasma estradiol and very high plasma gonadotropin levels. Galactose-free diet was started at 9 months of age in the first case and soon after birth in the second. Several similar cases have been recently reported. Primitive gonadal failure associated with galactosemia suggests a possible toxic' destruction of the ovaries during the intrauterine life by a galactose metabolite.
Similar articles
-
Ovarian failure in a young woman with galactosaemia.Ulster Med J. 1985 Oct;54(2):218-20. Ulster Med J. 1985. PMID: 4095816 Free PMC article. No abstract available.
-
Hypergonadotropic hypogonadism in female patients with galactosemia.N Engl J Med. 1981 Apr 23;304(17):994-8. doi: 10.1056/NEJM198104233041702. N Engl J Med. 1981. PMID: 6782485
-
[Ovarian insufficiency in congenital galactosemia].Presse Med. 1984 Dec 8;13(44):2685-7. Presse Med. 1984. PMID: 6240032 French.
-
Galactosemia and amenorrhea in the adolescent.Ann N Y Acad Sci. 2008;1135:112-7. doi: 10.1196/annals.1429.038. Ann N Y Acad Sci. 2008. PMID: 18574215 Review.
-
Delayed sexual maturation.Pediatrician. 1987;14(4):202-11. Pediatrician. 1987. PMID: 3331202 Review.
Cited by
-
Primary ovarian insufficiency in classic galactosemia: current understanding and future research opportunities.J Assist Reprod Genet. 2018 Jan;35(1):3-16. doi: 10.1007/s10815-017-1039-7. Epub 2017 Sep 20. J Assist Reprod Genet. 2018. PMID: 28932969 Free PMC article. Review.
-
Dietary lactose intake, lactose intolerance, and the risk of epithelial ovarian cancer in southern Ontario (Canada).Cancer Causes Control. 1994 Nov;5(6):540-8. doi: 10.1007/BF01831382. Cancer Causes Control. 1994. PMID: 7827241
-
Ovarian failure in a young woman with galactosaemia.Ulster Med J. 1985 Oct;54(2):218-20. Ulster Med J. 1985. PMID: 4095816 Free PMC article. No abstract available.
-
Fertility preservation in female classic galactosemia patients.Orphanet J Rare Dis. 2013 Jul 16;8:107. doi: 10.1186/1750-1172-8-107. Orphanet J Rare Dis. 2013. PMID: 23866841 Free PMC article. Review.
-
Gonadal function in galactosemics and in galactose-intoxicated animals.Eur J Pediatr. 1995;154(7 Suppl 2):S14-20. doi: 10.1007/BF02143797. Eur J Pediatr. 1995. PMID: 7671957 Review.