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. 1982 Sep;14(3):453-5.
doi: 10.1111/j.1365-2125.1982.tb02008.x.

The pharmacokinetics and bioavailability of mebendazole in man: a pilot study using [3H]-mebendazole

M Dawson, R J Allan, T R Watson

The pharmacokinetics and bioavailability of mebendazole in man: a pilot study using [3H]-mebendazole

M Dawson et al. Br J Clin Pharmacol. 1982 Sep.

Abstract

Following the intravenous administration of a tracer dose (1.7 microgram) of [3H]-mebendazole to a man, an elimination half-life of 1.16 h was observed and the volume of distribution was calculated to be 2.03 l/kg. After oral administration of the same dose, an elimination half-life of 0.74 h was observed. The bioavailability of mebendazole from the solution was found to be 17%.

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