Comparative Study
doi: 10.1136/jmg.15.4.249.
Calculation of genetic risks in Duchenne muscular dystrophy by geneticists in the United Kingdom
- PMID: 712756
- PMCID: PMC1013692
- DOI: 10.1136/jmg.15.4.249
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Comparative Study
Calculation of genetic risks in Duchenne muscular dystrophy by geneticists in the United Kingdom
J Med Genet.
1978 Aug.
Abstract
Pedigrees of Duchenne muscular dystrophy were sent to 32 geneticists in the United Kingdom, asking for their calculations for genetic risks for female relatives. Eighteen participated, of whom only 7 gave correct answers for all pedigrees. The method most used for calculations (the 'Bayesian' method) was most liable to errors in new situations. An alternative, simpler method is presented.
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