Comparative Study
Chromosomal aberrations in Chinese hamster cells exposed in vitro to tritium-labelled thymidine or x-rays at--196 degrees C
- PMID: 7128208
Item in Clipboard
Comparative Study
Chromosomal aberrations in Chinese hamster cells exposed in vitro to tritium-labelled thymidine or x-rays at--196 degrees C
Cytobios.
1982.
Abstract
A comparison was made between the incidence of chromosomal aberrations in G2-phase first division Chinese hamster cells exposed to tritium labelled thymidine (dose range 54-522 rad) or to 250 kV X-rays (dose range 98-711 rad) at--196 degrees C. The dose-response relationship for chromatid aberrations, expressed as breaks per cell, appeared to be linear for intranuclear tritium whereas that for X-rays was curvilinear. For the dose range studied, cells exposed to X-rays were markedly less sensitive than tritium-incorporated cells where a transmutation effect may operate.
Similar articles
-
Correlation of chromosomal aberrations and sister chromatid exchanges in individual CHO cells pre-labelled with BrdU and treated with DNaseI or X-rays.Int J Radiat Biol. 2002 Nov;78(11):1037-44. doi: 10.1080/09553000210166598. Int J Radiat Biol. 2002. PMID: 12456291
-
Distribution of radiation-induced G1 exchange and terminal deletion breakpoints in Chinese hamster chromosomes as detected by G banding.Int J Radiat Biol. 1994 Dec;66(6):747-55. Int J Radiat Biol. 1994. PMID: 7814973
-
Hyperthermic radiosensitization of synchronous Chinese hamster cells: relationship between lethality and chromosomal aberrations.Radiat Res. 1978 Oct;76(1):48-59. Radiat Res. 1978. PMID: 569879 No abstract available.
-
Revell revisited.Mutat Res. 1991 Sep-Oct;250(1-2):307-17. doi: 10.1016/0027-5107(91)90186-r. Mutat Res. 1991. PMID: 1944346 Review.
-
Synthesis and characterization of tritium-labelled substances.Appl Radiat Isot. 2018 Jul;137:261-272. doi: 10.1016/j.apradiso.2018.02.029. Epub 2018 Mar 8. Appl Radiat Isot. 2018. PMID: 29684631 Review.