doi: 10.1136/jnnp.45.8.669.
Linkage of autosomal dominant type I hereditary motor and sensory neuropathy to the Duffy locus on chromosome 1
- PMID: 7130990
- PMCID: PMC1083154
- DOI: 10.1136/jnnp.45.8.669
Item in Clipboard
Linkage of autosomal dominant type I hereditary motor and sensory neuropathy to the Duffy locus on chromosome 1
J Neurol Neurosurg Psychiatry.
1982 Aug.
Abstract
Data from English families confirms the probable linkage of the loci for autosomal dominant type I hereditary motor and sensory neuropathy (HMSN) and the Duffy blood group. The locus for autosomal dominant type I HMSN is in chromosome 1 near the centromere, about 15 centimorgans from the Duffy locus. The linkage between type I HMSN and the Duffy locus and the two recombinants found between Duffy and type II HMSN support the hypothesis that there are at least two genetic variants of autosomal dominant HMSN.
Similar articles
-
Genetic linkage evidence for heterogeneity in Charcot-Marie-Tooth neuropathy (HMSN type I).Ann Neurol. 1983 Dec;14(6):679-84. doi: 10.1002/ana.410140612. Ann Neurol. 1983. PMID: 6651251
-
Genetic linkage relationships of Charcot-Marie-Tooth disease (HMSN-Ib) to chromosome 1 markers.Neurology. 1987 Feb;37(2):325-9. doi: 10.1212/wnl.37.2.325. Neurology. 1987. PMID: 3468376
-
Evidence for linkage of Charcot-Marie-Tooth neuropathy to the Duffy locus on chromosome 1.Am J Hum Genet. 1982 May;34(3):388-94. Am J Hum Genet. 1982. PMID: 6952764 Free PMC article.
-
Hereditary motor-sensory neuropathies. Charcot-Marie-Tooth syndrome.Neurol Clin. 1989 Feb;7(1):9-23. Neurol Clin. 1989. PMID: 2646524 Review.
-
[The genetics of type 1 Charcot-Marie-Tooth disease, the hereditary focal neuropathies and the hereditary distal motor neuropathies].Rev Neurol. 2000 Jan 1-15;30(1):71-9. Rev Neurol. 2000. PMID: 10743001 Review. Spanish.
Cited by
-
Chromosome I linkage studies in Charcot-Marie-Tooth neuropathy type I.Am J Hum Genet. 1988 May;42(5):756-71. Am J Hum Genet. 1988. PMID: 2895983 Free PMC article.
-
Genetic linkage and heterogeneity in type I Charcot-Marie-Tooth disease (hereditary motor and sensory neuropathy type I).Am J Hum Genet. 1990 Dec;47(6):915-25. Am J Hum Genet. 1990. PMID: 2239969 Free PMC article.
-
Linkage of hereditary motor and sensory neuropathy type I to the pericentromeric region of chromosome 17.Am J Hum Genet. 1990 Jan;46(1):92-4. Am J Hum Genet. 1990. PMID: 2294757 Free PMC article.
-
Duplication within chromosome 17p11.2 in 12 families of French ancestry with Charcot-Marie-Tooth disease type 1a. The French CMT Research Group.J Med Genet. 1992 Nov;29(11):807-12. doi: 10.1136/jmg.29.11.807. J Med Genet. 1992. PMID: 1453432 Free PMC article.
-
Familial Scheuermann disease: a genetic and linkage study.J Med Genet. 1992 Jan;29(1):41-5. doi: 10.1136/jmg.29.1.41. J Med Genet. 1992. PMID: 1552543 Free PMC article.
References
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
