Identification of the cap binding protein of influenza virus
- PMID: 7133998
- PMCID: PMC321130
- DOI: 10.1093/nar/10.15.4803
Identification of the cap binding protein of influenza virus
Abstract
The presence of a cap binding protein in influenza virus PR8 has recently been demonstrated by photoaffinity labelling with the cap-analogue (gamma [3 2P]-[4-(benzoylphenyl)methylamido]-7-methylguanosine 5'-triphosphate). This paper describes the identification of the labelled protein using two-dimensional gel electrophoresis. The protein is shown to be PB2, the smaller of the two basic P proteins in the polymerase complex.
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