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Clinical Trial
. 1982 Nov;14(5):691-4.
doi: 10.1111/j.1365-2125.1982.tb04958.x.

Variations in responses to non-steroidal anti-inflammatory drugs

D L Scott, S Roden, T Marshall, M J Kendall
Clinical Trial

Variations in responses to non-steroidal anti-inflammatory drugs

D L Scott et al. Br J Clin Pharmacol. 1982 Nov.

Abstract

1 This paper assesses the variability in the response of patients with rheumatoid disease to a group of non-steroidal anti-inflammatory drugs (NSAID). 2 Thirty six patients were divided into three groups and each group received a set of four NSAID. The different drugs were each given three times daily for a week and the treatment order was randomised. 3 The study demonstrated marked variability and unpredictability in patient responses and cast doubt on the value of comparative trials of different NSAID.

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