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. 1982 Aug;2(8):561-7.
doi: 10.1007/BF01314216.

Autofluorescence as an index of ageing in human fibroblasts in culture

S I Rattan, K D Keeler, J H Buchanan, R Holliday

Autofluorescence as an index of ageing in human fibroblasts in culture

S I Rattan et al. Biosci Rep. 1982 Aug.

Abstract

An exponential increase in autofluorescence (AF) during serial passaging of human diploid fibroblasts, strain MRC-5, was observed using a fluorescence-activated cell sorter. Skin fibroblasts from patients with premature-ageing syndromes had high levels of AF, whereas virus-transformed cell lines had negligible amounts of AF.

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