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. 1982 Dec 15;50(12):2810-4.
doi: 10.1002/1097-0142(19821215)50:12<2810::aid-cncr2820501220>3.0.co;2-6.

Re-irradiation with interstitial implant for recurrent pelvic malignancies

A A Puthawala, A M Syed, P A Fleming, P J DiSaia

Re-irradiation with interstitial implant for recurrent pelvic malignancies

A A Puthawala et al. Cancer. .

Abstract

Forty patients with a diagnosis of recurrent pelvic malignancy from various primary sites with no clinical evidence of distant metastasis were re-irradiated with interstitial implant. Removable after-loading 192Ir sources or permanent 125I seeds or a combination of both were used. Twenty-six of these patients received interstitial implant at the time of exploratory laparotomy. A complete local control of implanted pelvic tumors was achieved in 27 of the 40 patients (67%). Thirteen of the 40 patients (33%) remained alive and disease-free to a minimum follow-up period of two years. Serious complications such as soft tissue necrosis and fistulae occurred in 15% of the patients.

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