Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1982 Nov;50(2):298-302.

Antibodies cross-reactive with DNA and cardiolipin in patients with systemic lupus erythematosus

T Koike, H Tomioka, A Kumagai

Antibodies cross-reactive with DNA and cardiolipin in patients with systemic lupus erythematosus

T Koike et al. Clin Exp Immunol. 1982 Nov.

Abstract

Using a modified solid phase radioimmunoassay (RIA), sera from 11 patients with systemic lupus erythematosus (SLE) that had high DNA binding activities were analysed for their ability to cross-react with phospholipids. Polyspecific anti-DNA antibodies that reacted with both ssDNA and dsDNA had the ability to cross-react with phospholipids, especially cardiolipin. The relationship between biological false-positive serological tests for syphilis (BFP-STS) and the magnitude of serum anti-DNA antibody levels is also discussed.

PubMed Disclaimer

References

    1. J Clin Invest. 1967 Nov;46(11):1867-82 - PubMed
    1. Br J Vener Dis. 1969 Sep;45(3):202-4 - PubMed
    1. J Exp Med. 1971 Jul 1;134(1):294-312 - PubMed
    1. Acta Derm Venereol. 1972;52(3):196-200 - PubMed
    1. Anal Biochem. 1975 May 12;65(1-2):525-32 - PubMed

Publication types

LinkOut - more resources