Solid-phase radioimmunoassay for detection of plague antigen in animal tissue
- PMID: 7153344
- PMCID: PMC272508
- DOI: 10.1128/jcm.16.5.953-956.1982
Solid-phase radioimmunoassay for detection of plague antigen in animal tissue
Abstract
A rapid and sensitive radioimmunoassay for the detection of soluble Yersinia pestis fraction I antigen using antibody-coated beads and radiolabeled immunoglobulin was applied to spleen-liver extracts, rendered noninfectious by either treatment or filtration, from rodents dead of plague. The procedure was capable of detecting nanogram amounts of soluble plague antigen.
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