Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1982 Dec 27;150(2):314-8.
doi: 10.1016/0014-5793(82)80759-x.

Identification of the NH2-terminal blocking group of calcineurin B as myristic acid

A Aitken, P Cohen, S Santikarn, D H Williams, A G Calder, A Smith, C B Klee
Free article

Identification of the NH2-terminal blocking group of calcineurin B as myristic acid

A Aitken et al. FEBS Lett. .
Free article

Abstract

The NH2-terminal blocking group of the Ca2+-binding B-subunit of calcineurin (protein phosphatase-2B) has been identified as myristic acid by fast atom bombardment mass spectrometry and gas chromatography. The sequence, myristyl-Gly-Asn-Glu-Ala-, is very similar to that of the catalytic subunit of cyclic AMP-dependent protein kinase, the only other protein known to contain this fatty acid. This finding, and the elution of all myristyl peptides at 57% acetonitrile on reverse phase HPLC, may facilitate the identification of other proteins with this blocking group.

PubMed Disclaimer

Publication types

LinkOut - more resources