Capillary supply and cross-sectional area of slow and fast twitch muscle fibres in man

Abstract

The muscles triceps brachii, quadriceps femoris (part vastus lateralis) and soleus were analysed in 6 men and 6 women for fibre composition (% slow twitch, ST-fibres and % fast twitch, FT-fibres), fibre cross sectional areas, and capillarization. Also the fraction of fibres enclosed by their own fibre type was analysed together with the capillary supply of these fibres. Fibre composition was 39(19-60)% ST in m. triceps brachii, 60(29-78)% ST in m. vastus lateralis and 73(49-88)% ST in m. soleus. Fibre areas ranged from 2,320 to 16,667 microns2 being smallest in m. triceps brachii and largest in m. soleus (p less than 0.05) and with ST fibres being significantly smaller than FT fibres in some of the muscles. In all muscles the shape of the fibres was elliptical with the larger diameter being about twice the smaller diameter. Capillary density per cross sectional muscle area was not related to the fibre composition and was 379(302-500) cap/mm2 in m. triceps brachii, 404(284-529) cap/mm2 in m. vastus lateralis and 417(333-592) cap/mm2 in m. soleus. However, capillary supply expressed as fibre type area per capillary was up to 40% larger for FT-fibres than for ST-fibres within the same muscle (p less than 0.05). The capillary supply of enclosed fibres was not different from that of fibres surrounded also by the other fibre type. The results demonstrate that the difference in capillary supply to ST and FT-fibres is less distinct in humans than in other mammals, which is consistent with the metabolic potentials also being more alike.